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Bellafill® for Nasolabial Folds

In the longest and largest dermal filler study ever conducted, Bellafill® outperformed by demonstrating its safety and efficacy through 5 years after treatment. Uniquely formulated to meet the specific demands of filler-savvy patients, Bellafill® adds immediate volume to nasolabial folds and supports native collagen production long afterward.

82% of patients are very/extremely interested in a filler that would last up to 5 years.4

Your Patients

Nasolabial folds are among the earliest and most troublesome signs of aging, making them popular targets for dermal fillers. But the effectiveness of hyaluronic acid-based fillers is short-lived, and patients eventually develop needle or credit card “fatigue.” Bellafill® offers a solution for patients who don’t want to compromise between instant and long-lasting results. When patients trust their filler, they trust you, making you their first choice for other services.

A recent study showed that on average 47% of patients begin experiencing treatment fatigue after routinely receiving filler treatment for 3 or more years.4


Bellafill® is also FDA approved to treat moderate to severe atrophic, distensible acne scars.

Let’s talk about Bellafill®‘s role in your practice. Reach out to us to learn more.

Mechanism of Action

The unique formulation of Bellafill® creates a long-lasting improvement in skin. Its uniform 30 to 50 microns polymethyl methacrylate (PMMA) microspheres are suspended in a base of smooth collagen gel.

  • Bovine collagen gel (80%) adds immediate volume and lift to wrinkles and scars, smoothing them away for instant results
  • PMMA microspheres (20%) form a scaffold to support endogenous collagen production and tissue matrix formation3


Once injected, Bellafill® immediately adds volume to wrinkles. Over time, the PMMA microspheres form a scaffold that supports the growth of endogenous collagen. Over time, native collagen replaces the injected collagen and creates long-lasting results.

Bellafill is placed below the depression using a fine needle.

The injectable gel immediately adds volume to the skin to lift and smooth out wrinkles.4

Long-Term Satisfaction

Bellafill® is noted for its 5-year longevity, inspiring confidence among patients and making them more likely to turn to you for other services, such as peels or laser treatments. Bellafill® has been thoroughly evaluated, with 83% of subjects still reporting satisfaction at the 5-year mark.

80% of surveyed physicians would recommend Bellafill® to a patient seeking a filler with lasting results4

SM 2361-11 REV00

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